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Is glucose the scapegoat for tumor evasion?
Cancer Cell ( IF 48.8 ) Pub Date : 2021-07-12 , DOI: 10.1016/j.ccell.2021.06.006
Lydia N Raines 1 , Stanley Ching-Cheng Huang 2
Affiliation  

Tumor cells undergo rapid aerobic glycolysis to fuel growth and proliferation. A recent finding in Nature reveals that tumor-infiltrating myeloid cells demonstrate greater capacity for glucose uptake than tumor cells and consume significant amounts within the tumor milieu. Unexpectedly, tumor cells account for the highest glutamine utilization in the tumor microenvironment.



中文翻译:

葡萄糖是逃避肿瘤的替罪羊吗?

肿瘤细胞经历快速的有氧糖酵解以促进生长和增殖。《自然》杂志最近的一项发现表明,肿瘤浸润的骨髓细胞表现出比肿瘤细胞更大的葡萄糖摄取能力,并且在肿瘤环境中消耗大量葡萄糖。出乎意料的是,肿瘤细胞在肿瘤微环境中的谷氨酰胺利用率最高。

更新日期:2021-07-12
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