Biomass-derived monomers have received growing attention from sustainable polymer industry. Particularly, diol compounds can be formed from furfural (FAL) and 5-hydroxymethylfurfural (HMF). Herein, the mesoporous Cu–Al₂O₃ catalyst (meso-CuA) prepared by solvent-deficient precipitation was evaluated to be efficient in selective hydrogenation of FAL and HMF to furfuryl alcohol to 2,5-bis(hydroxymethyl)furan (BHMF), respectively, at temperatures of lower than 100 °C and high H₂ pressures. Owing to unique pore structure and small-sized copper nanoparticles entangled with alumina, meso-CuA turned out to be superior to other supported Cu catalysts in the hydrogenation of HMF to BHMF. Moreover, meso-CuA showed highly durable performance at the BHMF yield of higher than 90% at 100 °C, 50 bar H₂, and weight hourly space velocity of 0.2 h⁻¹ over time-on-stream of 100 h. The stability was also confirmed with the HMF feed containing 1 wt% of water that proved to have more considerable effect than other possible impurities. Centering around a catalytic reactor packed with meso-CuA, a process scheme from HMF feed to pure BHMF solid was developed at a production scale of 100 kg per day. The present results can contribute to designing commercial process of BHMF production from HMF and further, real biomass.

生物质衍生单体越来越受到可持续聚合物行业的关注。特别地，二醇化合物可以由糠醛(FAL)和5-羟甲基糠醛(HMF)形成。在此，通过溶剂缺陷沉淀法制备的介孔 Cu-Al ₂ O ₃催化剂（meso-CuA）被评估可有效地将 FAL 和 HMF 选择性加氢成糠醇成 2,5-双（羟甲基）呋喃（BHMF） , 分别在低于 100 °C 和高 H _{2 的}温度下压力。由于独特的孔结构和与氧化铝缠结的小尺寸铜纳米粒子，在 HMF 氢化成 BHMF 方面，meso-CuA 优于其他负载型 Cu 催化剂。此外，在 100 °C、50 bar H ₂和 0.2 h ^{-1 的}重时空速下，细观 CuA 表现出高度耐用的性能，BHMF 产率高于 90%超过 100 小时的在线时间。还证实了含有 1wt% 水的 HMF 进料的稳定性，这证明其比其他可能的杂质具有更显着的影响。以填充有中间型 CuA 的催化反应器为中心，开发了从 HMF 进料到纯 BHMF 固体的工艺方案，生产规模为每天 100 公斤。目前的结果有助于设计从 HMF 和进一步的真实生物质生产 BHMF 的商业过程。