Vonoprazan fumarate is a novel potassium-competitive acid blocker more effective in suppressing acid production than proton pump inhibitors (PPIs) and when combined with antibiotics has been used to eradicate Helicobacter pylori (H. pylori) infection. However, it has not yet been examined in an Australian setting. This study aimed to report on the efficacy and safety of vonoprazan-containing antibiotic combination therapies in the eradication of H. pylori.

中文翻译：

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抗生素与沃诺拉赞联合治疗幽门螺杆菌感染——探索性研究


Vonoprazan 富马酸盐是一种新型钾竞争性酸阻滞剂，比质子泵抑制剂 (PPI) 更能有效抑制酸的产生，与抗生素联合使用可根除幽门螺杆菌( H. pylori)感染。然而，它尚未在澳大利亚进行过审查。本研究旨在报告含有沃诺拉赞的抗生素联合疗法在根除幽门螺杆菌方面的有效性和安全性。幽门螺杆菌。