The presentation of chronic myeloid leukemia (CML) can be variable and related to the phase of the disease. It can manifest a wide range of symptoms and signs; ocular involvement is reported in patients with leukemia at the time of diagnosis. We describe ophthalmic manifestations as an initial presentation in patients with CML. We identified 38 publications between 1971 and 2020 describing ocular manifestations in CML. Ophthalmic problems occur either from direct or indirect infiltration of neoplastic cells or from secondary causes. Although nearly all ocular structures may be affected, leukemic retinopathy is the most frequent clinical manifestation. Others include iris infiltration, anterior uveitis, hypopyon, exudative/serous retinal detachment, and optic nerve infiltration.

慢性粒细胞白血病 (CML) 的表现可以是可变的并且与疾病的阶段有关。它可以表现出广泛的症状和体征；据报道，白血病患者在诊断时会出现眼部受累。我们将眼科表现描述为 CML 患者的初始表现。我们确定了 1971 年至 2020 年间描述 CML 眼部表现的 38 篇出版物。眼科问题是由肿瘤细胞的直接或间接浸润或继发性原因引起的。尽管几乎所有的眼部结构都可能受到影响，但白血病性视网膜病变是最常见的临床表现。其他包括虹膜浸润、前葡萄膜炎、前房积脓、渗出性/浆液性视网膜脱离和视神经浸润。