Scaffolds obtained from polycaprolactone (PCL) have received extensive explorations due to their biocompatibility and biomechanical features. Nevertheless, weak hydrophilicity limits their application for scaffold-aided tissue engineering. In this work, surface modification of PCL scaffolds by using the carbon dots (CDs) solutions was examined to increasing the hydrophilic property of PCL scaffolds. Mesenchymal cell growth followed up to further investigation and analysis on the biologic functions of the scaffolds. Our findings show an improvement in cell proliferation and attachment to the modified scaffold. The CD-based scaffold possessed surface roughness, pore structure, hydrophilicity, and biocompatibility. The procedural situation, structural manufacture, and optimizing the functionality were screened carefully. Thus, this practical technique of PCL modification gives more intelligent biomedical scaffolds and tissue engineering agents with adjustable designs and desirable performances.

从聚己内酯 (PCL) 获得的支架由于其生物相容性和生物力学特性而受到广泛的探索。然而，弱亲水性限制了它们在支架辅助组织工程中的应用。在这项工作中，研究了使用碳点 (CD) 溶液对 PCL 支架进行表面改性，以增加 PCL 支架的亲水性。间充质细胞生长跟进以进一步调查和分析支架的生物学功能。我们的研究结果表明，细胞增殖和对修饰支架的附着有所改善。CD基支架具有表面粗糙度、孔结构、亲水性和生物相容性。对程序情况、结构制造和功能优化进行了仔细筛选。因此，