The greener methodology to synthesize s-triazine derivatives (also known as TCT) is described, including synthesis through microwave, ultrasound, and solvent-free conditions. This review mainly focuses on reactions of TCT (2,4,6-trichloro-1,3,5-triazine) with various substituents having amine and hydroxy functionalities to give corresponding triazine derivatives under a greener approach. The results of reactions indicate that, unlike classical methods, green methods result in better yields of the product, through a rapid reaction, under mild reaction conditions, and by easy workup procedures.

中文翻译：

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合成具有生物活性的 s-三嗪 (TCT) 衍生物的更环保方法：最近的更新

描述了合成s-三嗪衍生物（也称为 TCT）的更环保的方法，包括通过微波、超声和无溶剂条件进行合成。本综述主要关注 TCT（2,4,6-三氯-1,3,5-三嗪）与各种具有胺和羟基官能团的取代基的反应，以更环保的方式得到相应的三嗪衍生物。反应结果表明，与经典方法不同，绿色方法通过快速反应、温和的反应条件和简单的后处理程序，可以提高产品的收率。