Abstract

Various benzothiazole derivatives were synthesized by allowing 2-cyanomethylbenzothiazole (1) or its arylidene derivatives to react with diverse reagents under different simple and efficient reaction conditions. The chemical structures of novel synthesized benzothiazole derivatives were affirmed by elemental analysis and different spectral data. The newly synthesized compounds were assessed as antibacterial agents against Staphylococcus aureus and Escherichia coli bacteria.

中文翻译：

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包含苯并噻唑部分的新型杂环化合物的合成及其抗菌评价

摘要

通过让2-氰基甲基苯并噻唑( 1)或其亚芳基衍生物在不同的简单有效的反应条件下与多种试剂反应合成了多种苯并噻唑衍生物。通过元素分析和不同的光谱数据确认了新型合成的苯并噻唑衍生物的化学结构。新合成的化合物被评估为抗金黄色葡萄球菌和大肠杆菌的抗菌剂。