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Oncogenesis by phase separation
Nature Reviews Genetics ( IF 39.1 ) Pub Date : 2021-07-09 , DOI: 10.1038/s41576-021-00396-y
Grant Otto 1
Affiliation  

A new study by Ahn et al. shows that chimeric proteins containing intrinsically disordered regions mediate oncogenesis by inducing liquid–liquid phase separation and thereby affecting chromatin conformation and transcription.

中文翻译:

通过相分离致癌

Ahn 等人的一项新研究。表明含有内在无序区域的嵌合蛋白通过诱导液-液相分离从而影响染色质构象和转录来介导肿瘤发生。
更新日期:2021-07-09
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