In this study, poly(3-methylthiophene) modified electrode as a voltammetric sensor was developed for the detection of florfenicol (FF). Firstly, for the modification of glassy carbon electrode (GCE), 3-methylthiophene (3-MTF) was polymerized in acetonitrile (AcN) containing tetrabutylammonium tetrafluoroborate (TBATFB) by cyclic voltammetry (CV) method. Then, in order to determine the florfenicol sensor property of 3-MTF modified GCE, parameters such as electrolyte type and electrolyte pH, scan rate, film thickness, pulse amplitude, and pulse width were investigated by using differential pulse voltammetry method (DPV). When the florfenicol responses of the modified electrode were compared to the unmodified GCE responses, it was found that the florfenicol selectivity, sensitivity, and response stability of the modified electrode were significantly increased. A linear calibration plot was obtained for florfenicol in the concentration range of 0.1–1.0 mM. From the linear calibration curve, the correlation coefficient (R² value), determination limit (LOD), and quantitation limit (LOQ) were calculated as 0.999, 0.0399 mM, and 0.1197 mM, respectively. In addition, analytical application of the developed sensor for the determination of florfenicol was carried out in red and chicken meat samples. The recovery efficiency for red and chicken meat samples was obtained from 90.07 to 111.92% by using 3-MTF modified GCE. As a result, an electrochemical sensor was developed for the florfenicol detection which is fast, simple, low cost, 98.72% reproducible, stable, sensitive, and selective.

在这项研究中，聚（3-甲基噻吩）修饰电极作为伏安传感器被开发用于检测氟苯尼考（FF）。首先，为了修饰玻碳电极（GCE），通过循环伏安法（CV）法在含有四丁基四氟硼酸铵（TBATFB）的乙腈（AcN）中聚合了3-甲基噻吩（3-MTF）。然后，为了确定 3-MTF 改性 GCE 的氟苯尼考传感器性能，使用差分脉冲伏安法 (DPV) 研究了电解质类型和电解质 pH 值、扫描速率、膜厚、脉冲幅度和脉冲宽度等参数。当将修饰电极的氟苯尼考响应与未修饰的 GCE 响应进行比较时，发现氟苯尼考的​​选择性、灵敏度、修饰电极的响应稳定性显着提高。获得了浓度范围为 0.1–1.0 mM 的氟苯尼考的​​线性校准图。从线性校准曲线，相关系数（R ²值）、测定限 (LOD) 和定量限 (LOQ) 分别计算为 0.999、0.0399 mM 和 0.1197 mM。此外，在红肉和鸡肉样品中进行了用于测定氟苯尼考的​​开发传感器的分析应用。通过使用 3-MTF 改进的 GCE，红肉和鸡肉样品的回收率从 90.07% 到 111.92%。因此，开发了一种用于氟苯尼考检测的电化学传感器，该传感器具有快速、简单、低成本、98.72% 重现性、稳定、灵敏和选择性的特点。