While published guidelines are useful in the care of patients with long-QT syndrome, it can be difficult to decide how to apply the guidelines to individual patients, particularly those with intermediate risk. We explored the diversity of opinion among 24 clinicians with expertise in long-QT syndrome. Experts from various regions and institutions were presented with 4 challenging clinical scenarios and asked to provide commentary emphasizing why they would make their treatment recommendations. All 24 authors were asked to vote on case-specific questions so as to demonstrate the degree of consensus or divergence of opinion. Of 24 authors, 23 voted and 1 abstained. Details of voting results with commentary are presented. There was consensus on several key points, particularly on the importance of the diagnostic evaluation and of β-blocker use. There was diversity of opinion about the appropriate use of other therapeutic measures in intermediate-risk individuals. Significant gaps in knowledge were identified.

中文翻译：

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先天性长 QT 综合征的管理：专家评论

虽然已发表的指南对长 QT 综合征患者的治疗很有用，但很难决定如何将指南应用于个体患者，尤其是中度风险患者。我们探讨了 24 位具有长 QT 综合征专业知识的临床医生的意见多样性。向来自不同地区和机构的专家展示了 4 种具有挑战性的临床情景，并要求他们发表评论，强调他们为何会提出治疗建议。所有 24 位作者都被要求就具体案例问题进行投票，以证明意见一致或分歧的程度。24 位作者中，23 人投了票，1 人弃权。附有评论的投票结果的详细信息。在几个关键点上达成了共识，特别是在诊断评估和 β 受体阻滞剂使用的重要性上。对于在中等风险个体中适当使用其他治疗措施存在不同意见。发现了知识上的重大差距。