Constipation is one of the most common functional gastrointestinal disorders and affects 20% of the general population. Irritable bowel syndrome (IBS) is a functional disorder of the gastrointestinal tract that affects the large intestine and is characterized by chronic abdominal pain and altered bowel habits. We report a case of a 35-year-old African American man with a past medical history of IBS who presented to the clinic with a chief complaint of abdominal pain and bloody diarrhea for 1 week. The patient stated that he used a colon-cleansing agent because of persistent constipation. Computed tomography scan of the patient’s abdomen and pelvis with contrast was performed which showed diffuse contiguous segmental mural thickening and nodularity seen along the distal transverse, descending, and sigmoid colon. Colonoscopy showed moderate diffuse inflammation characterized by altered vascularity, erythema, and granularity from the rectum to the descending colon, and localized mild inflammation characterized by erythema was found at the ileocecal valve. The patient’s clinical condition improved with symptomatic management over 10 days. Patients with IBS should be advised to restrain from using a colon-cleansing agent without advice from their primary doctor as it can lead to various complications.
Case Rep Gastroenterol 2021;15:621–625

中文翻译：

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结肠清洁剂诱发结肠炎

便秘是最常见的功能性胃肠道疾病之一，影响了 20% 的普通人群。肠易激综合征 (IBS) 是一种影响大肠的胃肠道功能障碍，其特征是慢性腹痛和排便习惯改变。我们报告了一个病例，一名 35 岁的非裔美国人有 IBS 既往病史，他到诊所就诊，主诉腹痛和血性腹泻 1 周。患者称他因持续便秘而使用结肠清洁剂。对患者的腹部和骨盆进行计算机断层扫描，显示沿远端横结肠、降结肠和乙状结肠可见弥漫性连续节段性壁增厚和结节。结肠镜检查显示中度弥漫性炎症，其特征是从直肠到降结肠的血管分布、红斑和粒度改变，在回盲瓣处发现以红斑为特征的局部轻度炎症。通过对症治疗 10 天，患者的临床状况有所改善。应建议 IBS 患者在没有初级医生建议的情况下避免使用结肠清洁剂，因为它会导致各种并发症。
Case Rep Gastroenterol 2021；15:621–625