The conceptual overlap between intolerance of uncertainty (IU) and anxiety sensitivity (AS) has gained recent attention, with researchers theorizing that IU may lead individuals to have greater difficulty tolerating the uncertainty about feared consequences of anxiety-related symptoms. Research has indicated that AS may mediate the relationship between IU and certain disorder-specific anxiety symptoms; however, it remains unclear if this relationship is consistent in a treatment-seeking sample of adults with transdiagnostic anxiety-related disorders. We hypothesized that there would be a significant indirect effect of IU, including both inhibitory and prospective subscales, on anxiety symptoms through greater levels of global AS, as well as specifically through physical and cognitive AS dimensions in a transdiagnostic sample of 287 treatment-seeking adults diagnosed with anxiety-related disorders. Partially consistent with hypotheses, there was a significant indirect effect of global IU on anxiety through global AS, as well as specifically through physical and cognitive, but not social, AS dimensions. There was also a significant indirect effect of prospective IU on anxiety through global AS and physical and cognitive, but not social, AS dimensions. There was no indirect effect of inhibitory IU on anxiety symptoms through AS. Findings suggest that AS may be one mechanism of the association between IU and increased anxiety symptoms transdiagnostically.

不确定性不容忍 (IU) 和焦虑敏感性 (AS) 之间的概念重叠最近引起了人们的关注，研究人员推测 IU 可能导致个人更难以忍受与焦虑相关症状的可怕后果的不确定性。研究表明 AS 可能介导 IU 与某些特定于疾病的焦虑症状之间的关系；然而，尚不清楚这种关系在患有跨诊断焦虑相关障碍的成人寻求治疗样本中是否一致。我们假设 IU 会通过更高水平的整体 AS 对焦虑症状产生显着的间接影响，包括抑制性和前瞻性子量表，以及特别是通过身体和认知 AS 维度在 287 名被诊断患有焦虑相关障碍的寻求治疗的成年人的跨诊断样本中。与假设部分一致，全局 IU 通过全局 AS 以及特别是通过身体和认知（而非社会）AS 维度对焦虑有显着的间接影响。预期 IU 还通过整体 AS 和身体和认知（但不是社会）AS 维度对焦虑产生显着的间接影响。抑制性 IU 通过 AS 对焦虑症状没有间接影响。研究结果表明，AS 可能是 IU 与跨诊断焦虑症状增加之间关联的一种机制。全局 IU 通过全局 AS 对焦虑有显着的间接影响，特别是通过身体和认知，而不是社会，AS 维度。预期 IU 还通过整体 AS 和身体和认知（但不是社会）AS 维度对焦虑产生显着的间接影响。抑制性 IU 通过 AS 对焦虑症状没有间接影响。研究结果表明，AS 可能是 IU 与跨诊断焦虑症状增加之间关联的一种机制。全局 IU 通过全局 AS 对焦虑有显着的间接影响，特别是通过身体和认知，而不是社会，AS 维度。预期 IU 还通过整体 AS 和身体和认知（但不是社会）AS 维度对焦虑产生显着的间接影响。抑制性 IU 通过 AS 对焦虑症状没有间接影响。研究结果表明，AS 可能是 IU 与跨诊断焦虑症状增加之间关联的一种机制。抑制性 IU 通过 AS 对焦虑症状没有间接影响。研究结果表明，AS 可能是 IU 与跨诊断焦虑症状增加之间关联的一种机制。抑制性 IU 通过 AS 对焦虑症状没有间接影响。研究结果表明，AS 可能是 IU 与跨诊断焦虑症状增加之间关联的一种机制。