Different ubiquitin chain types serve as distinct cellular signals. A new synthetic antigen-binding fragment, sAB-K29, specifically recognizes K29-linked diubiquitin and links K29 chains to proteotoxic stress and their accumulation in midbodies during mitosis.

中文翻译：

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将 K29-Ub 链与生物学联系起来

不同的泛素链类型充当不同的细胞信号。一种新的合成抗原结合片段 sAB-K29 可特异性识别 K29 连接的双泛素，并将 K29 链与蛋白毒性应激及其在有丝分裂期间在中间体中的积累联系起来。