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Immunotherapy in rare ovarian cancer.
Current Opinion in Oncology ( IF 2.8 ) Pub Date : 2021-07-06 , DOI: 10.1097/cco.0000000000000759
Tina Laga 1 , Ignace Vergote , Els Van Nieuwenhuysen
Affiliation  

Ovarian cancer (OC) is a heterogeneous disease and a mounting body of evidence shows that a 'one-size-fits-all' approach is obsolete. Differences in epidemiology, tumor biology, genetic profiles and treatment responses of these different types necessitate a tumor and patient-specific approach. Ninety percentage consists of epithelial OC with 70% being high-grade serous OC. The other rarer subtypes are low-grade serous (5%), clear cell (12%), endometrioid (11%) and mucinous carcinoma (3%). The remaining 10% are nonepithelial rare OCs: germ cell (3%) and sex-cord stromal tumors (7%).

中文翻译:

罕见卵巢癌的免疫治疗。

卵巢癌 (OC) 是一种异质性疾病,越来越多的证据表明“一刀切”的方法已经过时。这些不同类型的流行病学、肿瘤生物学、遗传谱和治疗反应的差异需要针对肿瘤和患者的具体方法。90% 为上皮性 OC,其中 70% 为高级别浆液性 OC。其他较罕见的亚型是低度浆液性癌(5%)、透明细胞癌(12%)、子宫内膜样癌(11%)和粘液性癌(3%)。其余 10% 是非上皮性罕见 OC:生殖细胞 (3%) 和性索间质瘤 (7%)。
更新日期:2021-07-09
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