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A consensus integrated care pathway for patients with primary biliary cholangitis: a guideline-based approach to clinical care of patients
Expert Review of Gastroenterology & Hepatology ( IF 3.8 ) Pub Date : 2021-07-07 , DOI: 10.1080/17474124.2021.1945919
Gideon M Hirschfield 1 , Olivier Chazouillères 2 , Helena Cortez-Pinto 3 , Guilherme Macedo 4 , Victor de Lédinghen 5 , Femi Adekunle 6 , Marco Carbone 7
Affiliation  

ABSTRACT

Introduction

Primary biliary cholangitis (PBC) is an infrequent, immune-mediated cholestatic liver disease, which can lead to liver fibrosis, cirrhosis and complications of end-stage liver disease. The established goals of treatment of PBC are prevention of end-stage liver disease and amelioration of associated symptoms. The European Association for the Study of the Liver (EASL) management guidelines provide extensive recommendations on the diagnosis and management of PBC.

Areas covered

This article describes the development by expert consensus of a ‘PBC Integrated Patient Care Pathway’ to simplify and standardize the management of PBC for clinicians based on current practice.

Expert opinion

Guideline adoption is potentially poor in practice since most patients with PBC in the community are seen by general gastroenterologists or hepatologists without a special interest in autoimmune liver disease. The PBC Integrated Patient Care Pathway is a best practice tool for clinicians designed to complement the EASL Clinical Practice Guidelines for the diagnosis and management of PBC patients. It gives clinicians a practical decision tree of the key steps in PBC management, thereby providing a simplified framework and an opportunity for more uniform practice that supports the safe and timely adoption of varied models of care provision to patients with PBC.



中文翻译:

原发性胆汁性胆管炎患者的共识综合护理途径:基于指南的患者临床护理方法

摘要

介绍

原发性胆汁性胆管炎 (PBC) 是一种罕见的、免疫介导的胆汁淤积性肝病,可导致肝纤维化、肝硬化和终末期肝病并发症。PBC 治疗的既定目标是预防终末期肝病和改善相关症状。欧洲肝脏研究协会 (EASL) 管理指南为 PBC 的诊断和管理提供了广泛的建议。

涵盖的领域

本文描述了“PBC 综合患者护理途径”的专家共识开发,以根据当前实践简化和规范临床医生的 PBC 管理。

专家意见

由于社区中的大多数 PBC 患者都是由对自身免疫性肝病没有特别兴趣的普通胃肠病学家或肝病学家看到的,因此在实践中采用指南可能很差。PBC 综合患者护理路径是临床医生的最佳实践工具,旨在补充 EASL 临床实践指南,用于 PBC 患者的诊断和管理。它为临床医生提供了 PBC 管理关键步骤的实用决策树,从而提供了一个简化的框架和一个更统一的实践机会,支持安全、及时地为 PBC 患者采用各种护理提供模式。

更新日期:2021-08-13
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