The novel coronavirus disease (COVID-19) pandemic outbreak is the most startling public health crises with attendant global socio-economic burden ever experienced in the twenty-first century. The level of devastation by this outbreak is such that highly impacted countries will take years to recover. Studies have shown that timely detection based on accelerated sample testing and accurate diagnosis are crucial steps to reducing or preventing the spread of any pandemic outbreak. In this opinionated review, the impacts of metal organic frameworks (MOFs) as a biosensor in a pandemic outbreak is investigated with reference to COVID-19. Biosensing technologies have been proven to be very effective in clinical analyses, especially in assessment of severe infectious diseases. Polymerase chain reactions (PCR, RT-PCR, CRISPR) - based test methods predominantly used for SARS-COV-2 diagnoses have serious limitations and the health scientists and researchers are urged to come up with a more robust and versatile system for solving diagnostic problem associated with the current and future pandemic outbreaks. MOFs, an emerging crystalline material with unique characteristics will serve as promising biosensing materials in a pandemic outbreak such as the one we are in. We hereby highlight the characteristics of MOFs and their sensing applications, potentials as biosensors in a pandemic outbreak and draw the attention of researchers to a new vista of research that needs immediate action.

新型冠状病毒病（COVID-19）大流行的爆发是二十世纪以来最令人震惊的公共卫生危机，并带来了全球社会经济负担。这次疫情造成的破坏程度如此之大，受影响严重的国家将需要数年时间才能恢复。研究表明，基于加速样本检测和准确诊断的及时检测是减少或防止任何大流行病爆发蔓延的关键步骤。在这篇固执己见的综述中，参考 COVID-19 研究了金属有机框架 (MOF) 作为生物传感器在大流行爆发中的影响。生物传感技术已被证明在临床分析中非常有效，特别是在评估严重传染病方面。主要用于 SARS-COV-2 诊断的基于聚合酶链反应（PCR、RT-PCR、CRISPR）的测试方法具有严重的局限性，因此敦促健康科学家和研究人员提出更强大和通用的系统来解决诊断问题与当前和未来的大流行爆发有关。MOFs是一种具有独特特性的新兴晶体材料，将在我们所处的大流行病爆发中作为有前途的生物传感材料。我们在此重点介绍MOFs的特性及其传感应用，以及在大流行病爆发中作为生物传感器的潜力，并引起人们的关注研究人员看到了需要立即采取行动的新研究前景。