Nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most common prescription drugs for inflammation, and topical NSAIDs are often used in ophthalmology to reduce pain, photophobia, inflammation, and edema. In recent years, many published reports have found that NSAIDs play an important role in the treatment of retinal neurodegenerative diseases, such as age-related macular degeneration (AMD), diabetic retinopathy (DR), glaucoma, pathological myopia, and retinitis pigmentosa (RP). The aim of the current review is to provide an overview of the role of various NSAIDs in the treatment of retinal neurodegenerative diseases and the corresponding mechanisms of action. This review highlighted that the topical application of NSAIDs for the treatment of retinal degenerative diseases has been studied to a remarkable extent and that its beneficial effects in many diseases have been proven. In the future, prospective studies with large study populations are required to extend these effects to clinical settings.

非甾体抗炎药 (NSAID) 是最常见的炎症处方药之一，外用 NSAID 常用于眼科以减轻疼痛、畏光、炎症和水肿。近年来，许多发表的报道发现，NSAIDs在视网膜神经退行性疾病的治疗中发挥着重要作用，如年龄相关性黄斑变性（AMD）、糖尿病视网膜病变（DR）、青光眼、病理性近视和色素性视网膜炎（RP ）。本综述的目的是概述各种非甾体抗炎药在治疗视网膜神经退行性疾病中的作用以及相应的作用机制。这篇综述强调了非甾体抗炎药在治疗视网膜退行性疾病中的局部应用已经得到了显着的研究，并且已经证明了它在许多疾病中的有益作用。将来，需要对大量研究人群进行前瞻性研究，以将这些影响扩展到临床环境。