The purpose of this study was to evaluate the phytochemicals, bactericidal activity, antioxidant capacity, and cytotoxicity of Aerva lanata flower extract. The results showed that methanol extract contains more number of phytochemicals (tannins, flavonoid, steroid, phenolics, quainones, and cumarin) than other solvent extracts. The increased concentration (40 mg mL⁻¹) of methanol extract showed excellent antibacterial activity against opportunistic bacterial pathogens Staphylococcus aureus (3–20 mm), Pseudomonas aeruginosa (9–25 mm), Salmonella species (10–23 mm), Streptococcus pneumoniae (3–16 mm), and Escherichia coli (10–24 mm). Furthermore, the methanol flower extract of A. lanata also possesses outstanding antioxidant activity at 1.48 ± 0.12 mg mL⁻¹. The methanol extract showed excellent nephroprotective activity (97.04 %) at 20 μg mL⁻¹ concentration on cisplatin (8 μg mL⁻¹) exposed HEK 293 cell line and it was almost comparable with the standard nephroprotective drug quercetin (8 μg mL⁻¹). These findings suggests that the methanol flower extract of A. lanata contains medically valuable bioactive molecules may be used as cure for significant health issues of human kind.

本研究的目的是评估Aerva lanata花提取物的植物化学物质、杀菌活性、抗氧化能力和细胞毒性。结果表明，与其他溶剂提取物相比，甲醇提取物含有更多的植物化学物质（单宁、黄酮类化合物、类固醇、酚类、醌类和香豆素）。甲醇提取物浓度增加 (40 mg mL ^-1 ) 对机会性细菌病原体金黄色葡萄球菌 (3–20 mm)、铜绿假单胞菌(9–25 mm)、沙门氏菌(10–23 mm)、肺炎链球菌显示出优异的抗菌活性（3-16 毫米）和大肠杆菌（10-24 毫米）。此外，甲醇花提取物A. lanata在 1.48 ± 0.12 mg mL ^{-1 时}也具有出色的抗氧化活性。甲醇提取物在 20 μg mL ^-1浓度下对暴露于 HEK 293 细胞系的顺铂 (8 μg mL ^-1 )显示出优异的肾保护活性 (97.04 %)，并且几乎与标准肾保护药物槲皮素 (8 μg mL ^-1 )相当. 这些发现表明，A. lanata的甲醇花提取物含有具有医学价值的生物活性分子，可用作治疗人类重大健康问题的方法。