MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression primarily at the post-transcriptional levels. It is now well established that miRNAs are crucial regulators of many developmental and physiological processes, including reproduction. In teleosts, expression profiling studies have shown that miRNAs are expressed in the fish ovary and their levels are regulated during follicle development and by hormones. Using CRISPR/Cas9 mediated gene knockout strategies, several recent studies have provided strong evidence that miR-202 and miR-200s on chromosome 23 play critical roles in regulating ovarian development, oogenesis, and ovulation. In this mini review, we provide a brief overview of canonical miRNA biogenesis and functions; summarize miRNAs that are expressed in fish ovary; and discuss the emerging role of miRNAs in regulating fish ovarian functions.

MicroRNA (miRNA) 是小的非编码 RNA，主要在转录后水平调节基因表达。现在已经确定 miRNA 是许多发育和生理过程（包括繁殖）的关键调节剂。在硬骨鱼中，表达谱研究表明 miRNA 在鱼卵巢中表达，并且它们的水平在卵泡发育过程中受到激素的调节。使用 CRISPR/Cas9 介导的基因敲除策略，最近的几项研究提供了强有力的证据，表明 23 号染色体上的 miR-202 和 miR-200 在调节卵巢发育、卵子发生和排卵中起关键作用。在这篇小评论中，我们简要概述了经典 miRNA 的生物发生和功能；总结在鱼卵巢中表达的 miRNA；