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Diastereoselective Synthesis of Morpholine Derivatives from Grignard Reagents and N-Sulfinyl Imines
Synlett ( IF 2 ) Pub Date : 2021-06-15 , DOI: 10.1055/a-1529-4797
Joseph M. Bateman , Diana Chan , Mustafa Moroglu , Benjamin F. Rahemtulla , Eric P. A. Talbot

The stereoselective synthesis of substituted morpholine derivatives has been achieved through a two-step process involving diastereoselective addition of a Grignard reagent to a sulfinyl imine, followed by cyclization.

中文翻译:

格氏试剂和 N-亚磺酰基亚胺非对映选择性合成吗啉衍生物

取代的吗啉衍生物的立体选择性合成是通过两步法实现的,包括将格氏试剂非对映选择性加成到亚磺酰基亚胺上,然后环化。
更新日期:2021-07-07
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