Omega-3 fatty acids for treating residual depressive symptoms in adult patients with bipolar disorder: A systematic review and meta-analysis of double-blind randomized, placebo-controlled trials,Bipolar Disorders

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Omega-3 fatty acids for treating residual depressive symptoms in adult patients with bipolar disorder: A systematic review and meta-analysis of double-blind randomized, placebo-controlled trials
Bipolar Disorders ( IF 5.0 ) Pub Date : 2021-07-06 , DOI: 10.1111/bdi.13115
Taro Kishi ₁ , Kenji Sakuma ₁ , Makoto Okuya ₁ , Masashi Ikeda ₁ , Nakao Iwata ₁

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The results of two previous meta-analyses, which examined whether omega-3 fatty acids (omega-3s), such as docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), improved residual depressive symptoms (RDSs) for bipolar disorder (BD) patients compared with placebo, were inconsistent (Table S1).^1,2 A study reported that omega-3 was superior to placebo¹; however, another did not.²

中文翻译：

Omega-3 脂肪酸用于治疗成年双相情感障碍患者的残余抑郁症状：双盲随机、安慰剂对照试验的系统评价和荟萃分析

先前两项荟萃分析的结果检查了二十二碳六烯酸 (DHA) 和二十碳五烯酸 (EPA) 等 omega-3 脂肪酸 (omega-3s) 是否能改善双相情感障碍 (BD) 的残余抑郁症状 (RDS)患者与安慰剂相比，不一致（表S1）。^1,2一项研究报告称，omega-3 优于安慰剂¹；但是，另一个没有。²

更新日期：2021-07-07

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