Cigarette smoking remains the leading behavioral risk factor for chronic disease and premature mortality. This RCT tested the efficacy of moderate intensity aerobic exercise as an adjunctive smoking cessation treatment among women. Participants (N = 105; age = 42.5, SD = 11.2) received brief smoking cessation counseling and 10 weeks of nicotine replacement therapy and were randomized to 12 weeks of moderate intensity exercise (Exercise; n = 53) or 12 weeks of health education (Control; n = 52). Longitudinal models, with Generalized Estimating Equations, showed no differences between Exercise and Control in cotinine-verified 7-day point prevalence abstinence (Wald = 1.96, p = 0.10) or continuous abstinence (Wald = 1.45, p = 0.23) at 12-weeks (post-treatment) or 6-, 9-, or 12-month follow-up, controlling for differences in baseline nicotine dependence. There was no effect of exercise on smoking cessation. The present study adds to the literature suggesting null effects of exercise as a smoking cessation adjunctive treatment despite promising findings in short-term laboratory based studies.

吸烟仍然是导致慢性病和过早死亡的主要行为风险因素。该随机对照试验测试了中等强度有氧运动作为女性辅助戒烟治疗的功效。参与者（N  = 105；年龄 = 42.5，SD = 11.2）接受了简短的戒烟咨询和 10 周的尼古丁替代疗法，并被随机分配到 12 周的中等强度运动（锻炼；n  = 53）或 12 周的健康教育（对照；n  = 52)。具有广义估计方程的纵向模型显示，在可替宁验证的 7 天点流行戒断 (Wald = 1.96, p  = 0.10) 或连续戒断 (Wald = 1.45, p = 0.23) 在 12 周（治疗后）或 6、9 或 12 个月的随访中，控制基线尼古丁依赖的差异。运动对戒烟没有影响。本研究补充了文献，表明运动作为戒烟辅助治疗无效，尽管在短期实验室研究中取得了有希望的发现。