Background: The approach for the determination of aminoimidazo-azaarenes (AIAs) is urgently required due to their mutagenic activity and potential carcinogenicity. For this purpose, a CdSe/ZnS quantum dots (CdSe/ZnS QDs)-embedded molecularly imprinted silica gel with high selectivity and sensitivity was successfully prepared and applied to analyze such target.

Methods: Herein, CdSe/ZnS QDs acted as the fluorescent probe, and molecularly imprinted silica gel as a recognition probe was synthesized on the surface of QDs via sol-gel method. 2- Aminobenzimidazole, which has a similar structure with AIAs, as well as low cost and low toxicity, was selected as the dummy template.

Results: The material has a high imprinting factor (IF=6.15); the linear range of CdSe/ZnS@MIP as a fluorescent sensing material for AIAs is 0.5-20.0 μg L^-1 with the limit of detection (LOD) of 0.25 μg L^-1 (3σ/s). Moreover, the fluorescent materials have been further applied to determine AIAs in beef floss and grilled fish fillet with satisfactory recoveries (82.8-110.8 %), and the relative standard deviation (RSD) is < 5.5%.

Conclusion: The proposed CdSe/ZnS QDs-embedded molecularly imprinted silica gel can be used to easily and selectively detect AIAs.

背景：氨基咪唑氮杂芳烃 (AIA) 具有致突变活性和潜在致癌性，因此迫切需要其测定方法。为此，成功制备了具有高选择性和灵敏度的 CdSe/ZnS 量子点 (CdSe/ZnS QDs) 嵌入分子印迹硅胶，并应用于分析此类目标。

方法：本文以CdSe/ZnS量子点作为荧光探针，通过溶胶-凝胶法在量子点表面合成分子印迹硅胶作为识别探针。2-氨基苯并咪唑与AIAs结构相似，成本低，毒性低，被选为虚拟模板。

结果：材料具有较高的压印因子（IF=6.15）；CdSe/ZnS@MIP 作为 AIA 的荧光传感材料的线性范围为 0.5-20.0 μg L ^-1，检测限 (LOD) 为 0.25 μg L ^-1 (3σ/s)。此外，荧光材料已进一步用于测定牛肉松和烤鱼片中的 AIA，回收率令人满意（82.8-110.8%），相对标准偏差 (RSD) < 5.5%。

结论：所提出的 CdSe/ZnS 量子点嵌入分子印迹硅胶可用于轻松和选择性地检测 AIA。