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Preparation and characterization of electrospun shape memory polyurethane/graphene quantum dot nanocomposite scaffolds for tissue engineering
International Journal of Polymeric Materials and Polymeric Biomaterials ( IF 2.5 ) Pub Date : 2021-07-06 , DOI: 10.1080/00914037.2021.1941954
Sanaz Sarabiyan Nejad 1 , Donya Razzaghi 2 , Mostafa Rezaei 2 , Massuomeh Bagheri 1 , Amin Babaie 2 , Farhang Abbasi 2
Affiliation  

Abstract

Shape memory polyurethane (SMPU)/graphene quantum dot nanoparticles (GQDs) nanofibers were prepared by electrospinning technique. Results show that the localization of GQD nanoparticles into the nanocomposite electrospun nanofibers has increased the nanofiber average diameter. An increment has been observed in the mechanical strength of nanocomposite nanofiber mats. More uniform and straight nanofibers have been obtained for PU-0.5% due to the relative electrical conductivity induced by the presence of GQD nanoparticles. Presence of crystallizable polycaprolactone (PCL) soft segment in PU structure induced shape memory potential in electrospun scaffolds. In vitro study showed PU-0.5% scaffold had good interaction with 3T3 fibroblast cells.



中文翻译:

用于组织工程的静电纺丝形状记忆聚氨酯/石墨烯量子点纳米复合材料支架的制备与表征

摘要

采用静电纺丝技术制备了形状记忆聚氨酯(SMPU)/石墨烯量子点纳米粒子(GQDs)纳米纤维。结果表明,GQD纳米粒子在纳米复合电纺纳米纤维中的定位增加了纳米纤维的平均直径。已观察到纳米复合纳米纤维垫的机械强度增加。由于 GQD 纳米粒子的存在引起的相对电导率,对于 PU-0.5% 获得了更均匀和直的纳米纤维。PU 结构中可结晶聚己内酯 (PCL) 软链段的存在诱导了静电纺丝支架中的形状记忆电位。体外研究表明PU-0.5%支架与3T3成纤维细胞有良好的相互作用。

更新日期:2021-07-06
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