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Association between Lipid Profiles and Renal Functions among Adults with Type 2 Diabetes
Dubai Diabetes and Endocrinology Journal Pub Date : 2019-01-01 , DOI: 10.1159/000502005
Salih Awla Hamzah

Introduction: Type 2 diabetes mellitus (T2DM) affects renal functions and lipid profiles of patients. Objectives: In this study, 100 patients (65 females, 35 males) with T2DM were evaluated to determine whether renal function characteristics and lipid profiles are associated with T2DM. Methods: Blood samples were collected from all patients with T2DM, and the levels of hemoglobin A1c (HbA1c), blood urea, serum creatinine, cholesterol, triglyceride (TGR), low-density lipoprotein (LDL), high-density lipoprotein (HDL), and very low-density lipoprotein (VLDL) were analyzed. Results: A direct correlation of blood sugar and HbA1c was observed with blood urea, serum creatinine, serum cholesterol, serum TGR, HDL, LDL, and VLDL. The results revealed elevated TGR levels in patients administered medications for hyperglycemia. Furthermore, serum TGR levels were significantly correlated with blood sugar levels (p = 0.035). Blood urea levels were significantly correlated with glycated hemoglobin (p = 0.008). Blood urea, serum creatinine, and serum cholesterol levels were highly significantly correlated with HbA1c (p = 0.008, 0.017, and 0.005, respectively), while HDL, LDL, and VLDL were not significantly correlated with HbA1c. Conclusion: This study highlights the importance of serum TGR and serum creatinine measurement for guiding the treatment of T2DM.

中文翻译:

成人 2 型糖尿病患者血脂水平与肾功能之间的关联

简介:2 型糖尿病 (T2DM) 会影响患者的肾功能和血脂状况。目的:在本研究中,对 100 名 T2DM 患者(65 名女性,35 名男性)进行了评估,以确定肾功能特征和脂质特征是否与 T2DM 相关。方法:采集所有T2DM患者的血样,测定血红蛋白A1c(HbA1c)、血尿素、血清肌酐、胆固醇、甘油三酯(TGR)、低密度脂蛋白(LDL)、高密度脂蛋白(HDL)水平。和极低密度脂蛋白 (VLDL) 进行了分析。结果:观察到血糖和 HbA1c 与血尿素、血清肌酐、血清胆固醇、血清 TGR、HDL、LDL 和 VLDL 之间存在直接相关性。结果显示,服用药物治疗高血糖症的患者的 TGR 水平升高。此外,血清 TGR 水平与血糖水平显着相关 (p = 0.035)。血尿素水平与糖化血红蛋白显着相关(p = 0.008)。血尿素、血清肌酐和血清胆固醇水平与 HbA1c 高度显着相关(分别为 p = 0.008、0.017 和 0.005),而 HDL、LDL 和 VLDL 与 HbA1c 没有显着相关性。结论:本研究强调了血清 TGR 和血清肌酐测量对指导 T2DM 治疗的重要性。和 VLDL 与 HbA1c 没有显着相关性。结论:本研究强调了血清 TGR 和血清肌酐测量对指导 T2DM 治疗的重要性。和 VLDL 与 HbA1c 没有显着相关性。结论:本研究强调了血清 TGR 和血清肌酐测量对指导 T2DM 治疗的重要性。
更新日期:2019-01-01
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