Background The aim of the study was to evaluate how different parameters in the preoperative, perioperative, and postoperative period affect time to full enteral feeding (TFEF) in children undergoing pyloromyotomy. Methods A retrospective study of all children operated for infantile hypertrophic pyloric stenosis between 2001 and 2017 was conducted. Parameters in demographics and in the preoperative and postoperative period were evaluated against TFEF (hours) using linear regression models. Results In the whole cohort of 175 children, mean TFEF was 47 hours with Standard Deviation (SD) of ±35. In the multivariate model, TFEF decreased with age [beta (B): −0.62; 95% confidence interval (95% CI) −1.05 to −0.19; p=0.005) and increased with the presence of severe underlying disease (congenital heart defect or syndrome) (B: 26.5; 95% CI 3.3 to 49.7; p=0.026). Hence, for every day of age, the time to fully fed decreased by 0.6 hour, and the presence of an underlying disease increased the time to fully fed with over one day. TFEF did not seem to be affected by prematurity, weight loss, symptom duration, preoperative acid/base balance or electrolyte values, surgical method, or method of postoperative feeding. Conclusions TFEF decreased with higher age and increased in children with a severe underlying disease. These results may be useful in providing adequate parental information regarding what affects TFEF and the length of hospital stay.

中文翻译：

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婴儿肥厚性幽门狭窄幽门肌切开术后完全肠内喂养时间的预测因素

背景 本研究的目的是评估术前、围手术期和术后期间的不同参数如何影响接受幽门肌切开术的儿童的完全肠内喂养时间 (TFEF)。方法回顾性分析2001年至2017年所有因小儿肥厚性幽门狭窄手术的患儿。使用线性回归模型根据 TFEF（小时）评估人口统计学参数以及术前和术后期间的参数。结果 在 175 名儿童的整个队列中，平均 TFEF 为 47 小时，标准差 (SD) 为 ±35。在多变量模型中，TFEF 随着年龄的增长而降低 [beta (B)：-0.62；95% 置信区间 (95% CI) -1.05 至 -0.19；p=0.005) 并随着严重基础疾病（先天性心脏病或综合征）的存在而增加（B：26.5；95% CI 3.3 至 49.7；p=0. 026). 因此，对于年龄的每一天，完全进食的时间减少了 0.6 小时，并且潜在疾病的存在使完全进食的时间增加了一天以上。TFEF 似乎不受早产、体重减轻、症状持续时间、术前酸/碱平衡或电解质值、手术方法或术后喂养方法的影响。结论 TFEF 随着年龄的增长而降低，并且在患有严重基础疾病的儿童中增加。这些结果可能有助于提供足够的关于影响 TFEF 和住院时间的因素的父母信息。术前酸/碱平衡或电解质值、手术方法或术后喂养方法。结论 TFEF 随着年龄的增长而降低，并且在患有严重基础疾病的儿童中增加。这些结果可能有助于提供足够的关于影响 TFEF 和住院时间的因素的父母信息。术前酸/碱平衡或电解质值、手术方法或术后喂养方法。结论 TFEF 随着年龄的增长而降低，并且在患有严重基础疾病的儿童中增加。这些结果可能有助于提供足够的关于影响 TFEF 和住院时间的因素的父母信息。