Water permeability of textile vascular grafts has been considered as a key indicator for predicting blood permeability after implantation. However, a correlation between water and blood permeability has not been established yet. Therefore, even though the water permeability of a vascular graft can be tested according to the standard ISO 7198, the results fail to guide a manufacturer or a surgeon to judge whether this vascular graft needs pre-clotting or not prior to implantation. As a result, all commercial graft products show almost zero water permeability, which leads to the loss of advantages that textile vascular grafts have the pore size-controlled porous wall. To solve this problem, four types of woven vascular grafts were designed and manufactured in the present work. Then their permeability to water, simulated plasma, and anticoagulated whole blood were measured at graded pressures from 8 to 16 kPa. Moreover, the correlations among the water permeability, the simulated plasma permeability, and the anticoagulated whole blood permeability were established. The results suggest that relatively steady correlations exist between the water permeability and the anticoagulated whole blood permeability, and that the evaluation of the blood permeability using the water permeability is feasible and objective. The present work provides a quantitative method for evaluating the blood permeability using the water permeability, and the latter is thus endowed with practical significance for guiding designs and clinical pre-clotting operations of textiles vascular grafts.

纺织血管移植物的透水性已被认为是预测植入后血液渗透性的关键指标。然而，尚未确定水和血液渗透性之间的相关性。因此，即使可以根据标准ISO 7198测试血管移植物的透水性，但结果无法指导制造商或外科医生判断该血管移植物在植入前是否需要预凝固。结果，所有商业移植产品的透水性几乎为零，这导致纺织血管移植物具有孔径可控的多孔壁的优势丧失。为了解决这个问题，在目前的工作中设计和制造了四种类型的编织血管移植物。然后它们对水的渗透性，模拟等离子体，在 8 至 16 kPa 的分级压力下测量抗凝全血。此外，还建立了水渗透性、模拟血浆渗透性和抗凝全血渗透性之间的相关性。结果表明，透水性与抗凝全血透性之间存在相对稳定的相关性，利用透水性评价血液通透性是可行和客观的。本工作提供了一种利用水渗透性评价血液渗透性的定量方法，对指导纺织品血管移植物的设计和临床预凝血操作具有实际意义。建立了水渗透性、模拟血浆渗透性和抗凝全血渗透性之间的相关性。结果表明，透水性与抗凝全血透性之间存在相对稳定的相关性，利用透水性评价血液通透性是可行和客观的。本工作提供了一种利用水渗透性评价血液渗透性的定量方法，对指导纺织品血管移植物的设计和临床预凝血操作具有实际意义。建立了水渗透性、模拟血浆渗透性和抗凝全血渗透性之间的相关性。结果表明，透水性与抗凝全血透性之间存在相对稳定的相关性，利用透水性评价血液通透性是可行和客观的。本工作提供了一种利用水渗透性评价血液渗透性的定量方法，因此后者对于指导纺织品血管移植物的设计和临床预凝血操作具有实际意义。结果表明，透水性与抗凝全血透性之间存在相对稳定的相关性，利用透水性评价血液通透性是可行和客观的。本工作提供了一种利用水渗透性评价血液渗透性的定量方法，对指导纺织品血管移植物的设计和临床预凝血操作具有实际意义。结果表明，透水性与抗凝全血透性之间存在相对稳定的相关性，利用透水性评价血液通透性是可行和客观的。本工作提供了一种利用水渗透性评价血液渗透性的定量方法，对指导纺织品血管移植物的设计和临床预凝血操作具有实际意义。