The study objective was to investigated the reliability and validity of the ADL-Glittre test (TGlittre) to assess the functional status of patients with interstitial lung disease (ILD). Twenty-one individuals with ILD participated (age: 63 ± 11 years; DLCO: 51.0 ± 12.6%predicted), evaluated with body plethysmography, Saint George Respiratory Questionnaire, modified Medical Research Council dyspnea scale, six-minute walk test (6MWT) and monitoring of physical activity of daily living. Two TGlittre were performed, with an interval of 30 minutes between them. The TGlittre demonstrated high test-retest reliability, with an intraclass correlation coefficient of 0.90 (95%CI: 0.75–0.96; p < 0.001). Nineteen patients (90.5%) performed better on the second test (mean difference between TGlittre 1 and 2: −0.57 ± 0.96 minute; p = 0.001), with a learning effect of 11.6%. The time in TGlittre correlated with 6MWT (r = −0.70; p = 0.002) and with the total energy expenditure in physical activity of daily living (r = −0.52; p = 0.02). In %predicted, TGlittre and 6MWT also correlated (r = −0.50; p = 0.04). Correlations were observed between TGlittre and pulmonary function variables (r = −0.47 to −0.57; p = 0.01 to p = 0.04). There was no difference in the physiological response between TGlittre 1 and 2, and between TGlittre and 6MWT (p > 0.05). In conclusion, the TGlittre is reliable and valid for assessing functional status of patients with ILD.

研究目的是调查 ADL-Glittre 测试 (TGlittre) 评估间质性肺疾病 (ILD) 患者功能状态的可靠性和有效性。 21 名 ILD 患者参与（年龄：63 ± 11 岁；DLCO：51.0 ± 12.6% 预测），通过身体体积描记法、圣乔治呼吸问卷、改良医学研究委员会呼吸困难量表、六分钟步行测试 (6MWT) 和监测日常生活的体力活动。进行了两次TGlittre，两次之间的间隔为30分钟。 TGlittre 表现出较高的重测可靠性，组内相关系数为 0.90（95%CI：0.75–0.96；p < 0.001）。 19 名患者 (90.5%) 在第二次测试中表现更好（TGlittre 1 和 2 之间的平均差异：-0.57 ± 0.96 分钟；p = 0.001），学习效果为 11.6%。 TGlittre 时间与 6MWT (r = -0.70; p = 0.002) 以及日常生活体力活动的总能量消耗 (r = -0.52; p = 0.02) 相关。在预测百分比中，TGlittre 和 6MWT 也相关（r = -0.50；p = 0.04）。观察到 TGlittre 和肺功能变量之间的相关性（r = -0.47 至 -0.57；p = 0.01 至 p = 0.04）。 TGlittre 1 和 2 之间以及 TGlittre 和 6MWT 之间的生理反应没有差异 (p > 0.05)。总之，TGlittre对于评估ILD患者的功能状态是可靠和有效的。