Abstract

Background

Coronary slow flow (CSF) is defined as the late progression of applied contrast through coronary arteries. The cardiac electrophysiological balance index (iCEB) reflects the balance between ventricular depolarisation and repolarisation and provides more information about ventricular arrhythmogenesis (VA) than other electrocardiography (ECG) parameters (QT, corrected QT [QTc], etc.).

Aim

We aimed to evaluate iCEB in patients with CSF.

Methods

We divided the study population into two groups as CSF and control. The CSF group consisted of 100 patients (33 female, 67 male, mean age 52.2 ± 2.6), while the control group consisted of the same number of age and sex-matched patients (35 female, 65 male, mean age 51.7 ± 1.4). ECG parameters of the study population (QRS duration, QT, T wave peak-to-end (Tp-e) intervals, iCEB (QT/QRS), and iCEBc (heart rate QTc/QRS) rates were calculated and compared between CSF and control groups.

Results

Intervals (QT and QTc intervals) and Tp-e/QTc ratio were greater in the CSF group compared with controls [422.1 ± 12.8 vs. 349.4 ± 14.3 bpm, respectively, p < .001; 457.0 ± 12.2 vs. 378.1 ± 12.3 bpm, respectively, p < .001, and 0.19 vs. 0.12, respectively, p < .001]. ICEB and iCEBc were significantly greater than controls [(4.9 ± 0.4 vs. 4.2 ± 0.4, respectively, p < .001), (5.7 ± 0.3 vs. 4.4 ± 0.3, respectively, p < .001)].

Conclusions

ICEB and iCEBc were significantly increased in patients with CSF. This may suggest that CSF may predispose to malign arrhythmias.

中文翻译：

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冠状动脉慢血流患者心电生理平衡指标评价

摘要

背景

冠状动脉慢血流 (CSF) 定义为通过冠状动脉应用造影剂的晚期进展。心脏电生理平衡指数 (iCEB) 反映了心室除极和复极之间的平衡，并提供了比其他心电图 (ECG) 参数（QT、校正 QT [QTc] 等）更多的关于室性心律失常 (VA) 的信息。

目标

我们旨在评估脑脊液患者的 iCEB。

方法

我们将研究人群分为两组，即脑脊液和对照组。CSF组由100名患者组成（33名女性，67名男性，平均年龄52.2±2.6），而对照组由相同数量的年龄和性别匹配的患者组成（35名女性，65名男性，平均年龄51.7±1.4） . 计算研究人群的心电图参数（QRS 持续时间、QT、T 波峰到终点 (Tp-e) 间隔、iCEB (QT/QRS) 和 iCEBc（心率 QTc/QRS）率），并在 CSF 和对照组。

结果

与对照组相比，CSF 组的间期（QT 和 QTc 间期）和 Tp-e/QTc 比值更大 [分别为 422.1 ± 12.8 对 349.4 ± 14.3 bpm，p < .001；分别为 457.0 ± 12.2 与 378.1 ± 12.3 bpm，p  < .001 和 0.19 与 0.12，分别为p < .001]。ICEB 和 iCEBc 显着高于对照组 [(4.9 ± 0.4 vs. 4.2 ± 0.4, p  < .001), (5.7 ± 0.3 vs. 4.4 ± 0.3, p  < .001)]。

结论

脑脊液患者的ICEB和iCEBc显着升高。这可能表明 CSF 可能易患恶性心律失常。