Activity of the growth hormone-releasing hormone antagonist MIA602 and its underlying mechanisms of action in sarcoidosis-like granuloma,Clinical & Translational Immunology

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Activity of the growth hormone-releasing hormone antagonist MIA602 and its underlying mechanisms of action in sarcoidosis-like granuloma
Clinical & Translational Immunology ( IF 5.8 ) Pub Date : 2021-07-05 , DOI: 10.1002/cti2.1310
Chongxu Zhang ₁ , Runxia Tian ₁ , Emilee M Dreifus ₂ , Abdolrazagh Hashemi Shahraki ₃ , Gregory Holt _{1,

3} , Renzhi Cai ₁ , Anthony Griswold ₄ , Pablo Bejarano ₅ , Robert Jackson _{1,

2} , Andrew V Schally _{6,

7} , Mehdi Mirsaeidi _{1,

3}

Affiliation

Growth hormone-releasing hormone (GHRH) is a potent stimulator of growth hormone (GH) secretion from the pituitary gland. Although GHRH is essential for the growth of immune cells, the regulatory effects of its antagonist in granulomatous disease remain unknown.

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