The 100 most-cited papers on age-related macular degeneration (AMD) were analysed using a bibliographic study. The bibliographic databases of the Institute for Scientific Information Web of Knowledge were searched, limited to research articles published between 1965 and 2020 in peer-reviewed journals. The papers were ranked in order of number of citations since publication. Five of the top 10 (and 3 of the top 4) papers reported randomised clinical trial results for either anti-vascular endothelial growth factor agents or nutritional supplements. Four of the top 10 papers reported genotype-phenotype associations between AMD and variants in Complement Factor H . This bibliographic study provides perspective and insight into many of the most influential contributions in the understanding and management of AMD and its evolution over time. All data relevant to the study are included in the article or uploaded as online supplemental information. All data relevant to the study are included in the article.

中文翻译：

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关于年龄相关性黄斑变性的 100 篇被引用次数最多的论文：文献视角


使用文献研究对 100 篇被引用最多的有关年龄相关性黄斑变性 (AMD) 的论文进行了分析。检索了科学信息研究所的书目数据库，仅限于 1965 年至 2020 年在同行评审期刊上发表的研究文章。论文按发表后被引用次数的顺序排列。前 10 名论文中的 5 篇（前 4 名论文中的 3 篇）报告了抗血管内皮生长因子药物或营养补充剂的随机临床试验结果。排名前 10 的论文中有 4 篇报道了 AMD 与补体因子 H 变异之间的基因型-表型关联。本文献研究提供了对 AMD 的理解和管理及其随时间演变的许多最有影响力的贡献的观点和见解。与研究相关的所有数据都包含在文章中或作为在线补充信息上传。与该研究相关的所有数据都包含在文章中。