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Biometric and ICL-related risk factors associated to sub-optimal vaults in eyes implanted with implantable collamer lenses
Eye and Vision ( IF 4.1 ) Pub Date : 2021-07-05 , DOI: 10.1186/s40662-021-00250-6
Santiago Cerpa Manito 1 , Angel Sánchez Trancón 1 , Oscar Torrado Sierra 1 , António Manuel Baptista 2 , Pedro Miguel Serra 1, 3
Affiliation  

To identify biometric and implantable collamer lens (ICL)-related risk factors associated with sub-optimal postoperative vault in eyes implanted with phakic ICL. This study reports a retrospective case series of the first operated eye in 360 patients implanted with myopic spherical or toric ICL. Preoperatively, white-to-white (WTW), central keratometry (Kc) and central corneal thickness (CCT) were measured using the Pentacam. Anterior-segment optical coherence tomography (AS-OCT, Visante) was applied preoperatively for measuring the horizontal anterior-chamber angle-to-angle distance (ATA), internal anterior chamber depth (ACD), crystalline lens rise (CLR), anterior-chamber angle (ACA) and postoperatively the vault. Eyes were divided into three vault groups: low (LVG: ≤ 250 μm), optimal (OVG: > 250 and < 1000 μm) and high (HVG: ≥ 1000 μm). Multinomial logistic regression (MLR) was used to find the sub-optimal vault predictors. MLR showed that CLR, ICL size minus the ATA (ICL size-ATA), age, ICL spherical equivalent (ICLSE) and ICL size as contributing factors for sub-optimal vaults (pseudo-R2 = 0.40). Increased CLR (OR: 1.01, CI: 1.00–1.01) and less myopic ICLSE (OR: 1.22, CI: 1.07–1.40) were risk factors for low vaults. Larger ICL size-ATA (OR: 41.29, CI: 10.57–161.22) and the 13.7 mm ICL (OR: 7.08, CI: 3.16–15.89) were risk factors for high vaults, whereas less myopic ICLSE (OR: 0.85, CI: 0.76–0.95) and older age (OR: 0.92, CI: 0.88–0.98) were protective factors. High CLR and low ICLSE were the major risk factors in eyes presenting low vaults. In the opposite direction, ICL size-ATA was the major contributor for high vaults. This relationship was more critical in higher myopic ICLSE, younger eyes and when 13.7 mm ICL were used. The findings show that factors influencing the vault have differentiated weight of influence depending on the type of vault (low, optimal or high).

中文翻译:

与植入可植入式准分子镜片的眼睛的次优拱顶相关的生物识别和 ICL 相关风险因素

确定与植入有晶状体晶体 ICL 的眼的次优术后穹窿相关的生物特征和植入式可植入式晶状体晶状体 (ICL) 相关风险因素。本研究报告了 360 名植入近视球形或环面 ICL 的患者首次手术眼的回顾性病例系列。术前,使用 Pentacam 测量白到白 (WTW)、中央角膜曲率 (Kc) 和中央角膜厚度 (CCT)。术前应用前段光学相干断层扫描(AS-OCT,Visante)测量水平前房角距(ATA)、前房内深度(ACD)、晶状体上升(CLR)、前房角距房角 (ACA) 和术后穹窿。眼睛分为三个拱顶组:低(LVG:≤ 250 μm)、最佳(OVG:> 250 和 < 1000 μm)和高(HVG:≥ 1000 μm)。多项逻辑回归 (MLR) 用于找到次优的金库预测器。MLR 显示 CLR、ICL 尺寸减去 ATA(ICL 尺寸-ATA)、年龄、ICL 球面当量(ICLSE)和 ICL 尺寸是次优金库的影响因素(伪 R2 = 0.40)。CLR 增加(OR:1.01,CI:1.00-1.01)和近视 ICLSE 减少(OR:1.22,CI:1.07-1.40)是低拱顶的危险因素。较大的 ICL 尺寸-ATA(OR:41.29,CI:10.57-161.22)和 13.7 mm ICL(OR:7.08,CI:3.16-15.89)是高拱的危险因素,而近视度较低的 ICLSE(OR:0.85,CI: 0.76–0.95) 和年龄较大 (OR: 0.92, CI: 0.88–0.98) 是保护因素。高 CLR 和低 ICLSE 是低拱形眼的主要危险因素。在相反的方向上,ICL size-ATA 是高金库的主要贡献者。这种关系在高度近视的 ICLSE、年轻的眼睛和使用 13.7 mm ICL 时更为重要。研究结果表明,影响金库的因素根据金库的类型(低、最佳或高)具有不同的影响权重。
更新日期:2021-07-05
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