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Peripheral neuropathy after viral eradication with direct-acting antivirals in chronic HCV hepatitis: A prospective study
Liver International ( IF 6.0 ) Pub Date : 2021-07-05 , DOI: 10.1111/liv.15002
Maria M Zanone 1 , Claudia Marinucci 1 , Alessia Ciancio 2 , Dario Cocito 3 , Federica Zardo 1 , Emanuela Spagone 3 , Bruno Ferrero 3 , Cristina Cerruti 1 , Lorena Charrier 4 , Franco Cavallo 4 , Giorgio M Saracco 2 , Massimo Porta 1
Affiliation  

HCV-related extra-hepatic complications include peripheral neuropathies, with important prevalence and impact. A recent metanalysis of previous intervention trials concluded for insufficient data to support evidence-based treatments for this complication. In this longitudinal study, we assessed for the first time prevalence and outcome of neuropathy in a cohort of patients with chronic HCV, before and after direct-acting antiviral agent (DAA) treatment.

中文翻译:


慢性丙型肝炎使用直接作用抗病毒药物根除病毒后周围神经病变:一项前瞻性研究



HCV 相关的肝外并发症包括周围神经病变,具有重要的患病率和影响。最近对之前的干预试验进行的荟萃分析得出的结论是,数据不足以支持这种并发症的循证治疗。在这项纵向研究中,我们首次评估了一组慢性丙型肝炎患者在直接作用抗病毒药物(DAA)治疗前后神经病变的患病率和结果。
更新日期:2021-07-05
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