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Chemical constituents from the leaves and branches of Annona coriacea Mart. (Annonaceae)
Biochemical Systematics and Ecology ( IF 1.4 ) Pub Date : 2021-07-04 , DOI: 10.1016/j.bse.2021.104297
Giovanna Nogueira da Silva Avelino Oliveira Rocha 1 , Lívia Macedo Dutra 1 , Weider Henrique Pinheiro Paz 2 , Felipe Moura Araujo da Silva 2 , Emmanoel Vilaça Costa 2 , Jackson Roberto Guedes da Silva Almeida 1
Affiliation  

The phytochemical investigation of the leaves and branches of Annona coriacea Mart. (Annonaceae) led to the isolation and characterization of eight compounds: five isoquinoline-derived alkaloids, including pukateine (1), liriodenine (4), anonaine (5), obovanine (6), and norisocorydine (7); one terpene lactone known as loliolide (3); one benzoic acid derivative, 2-methoxybenzoic acid (2), and 3,4,5-trimethoxyphenol (8). All compounds, except liriodenine, are being described for the first time in the species A. coriacea, and their chemophenetics relationships were discussed. The structures were elucidated by extensive analyses of 1D and 2D NMR (COSY, HSQC, and HMBC) spectroscopy in combination with MS, and the data were compared with literature values. The NMR dataset of pukateine and obovanine was reviewed. Our results showed that A. coriacea is a typical species of the Annonaceae family and an important source of aporphine alkaloids with chemophenetic relationships with Xylopia, Duguetia, Guatteria, Artabotrys, and Goniothalamus genera.



中文翻译:

Annona coriacea Mart叶子和树枝的化学成分。(番荔枝科)

番荔枝叶和枝条的植物化学研究。(番荔枝)导致的分离和的八种化合物的表征:5异喹啉衍生的生物碱,包括pukateine(1),liriodenine(4),anonaine(5),obovanine(6),和norisocorydine(7); 一种被称为 loliolide ( 3 ) 的萜内酯;一种苯甲酸衍生物、2-甲氧基苯甲酸( 2 )和3,4,5-三甲氧基苯酚( 8 )。除鹅掌楸外,所有化合物均首次在A. coriacea物种中得到描述并讨论了它们的化学现象学关系。通过 1D 和 2D NMR(COSY、HSQC 和 HMBC)光谱结合 MS 的广泛分析阐明了结构,并将数据与文献值进行了比较。审查了 pukateine 和 obovanine 的 NMR 数据集。我们的研究结果表明,A. coriacea是番荔枝科的典型物种,是阿朴啡类生物碱的重要来源,与XylopiaDuguetiaGuatteriaArtabotrysGoniothalamus属具有趋化关系。

更新日期:2021-07-04
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