Interleukin-1 pathway in active large vessel vasculitis patients with a poor prognosis: a longitudinal transcriptome analysis,Clinical & Translational Immunology

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Interleukin-1 pathway in active large vessel vasculitis patients with a poor prognosis: a longitudinal transcriptome analysis
Clinical & Translational Immunology ( IF 4.6 ) Pub Date : 2021-07-02 , DOI: 10.1002/cti2.1307
Kotaro Matsumoto ₁ , Katsuya Suzuki ₁ , Keiko Yoshimoto ₁ , Sho Ishigaki ₁ , Hiroto Yoshida ₂ , Mayu Magi ₂ , Yoshihiro Matsumoto ₂ , Yuko Kaneko ₁ , Tsutomu Takeuchi ₁

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Large vessel vasculitis (LVV) is characterised by a high relapse rate. Because accurate assessment of the LVV disease status can be difficult, an accurate prognostic marker for initial risk stratification is required. We conducted a comprehensive longitudinal investigation of next-generation RNA-sequencing data for patients with LVV to explore useful biomarkers associated with clinical characteristics.

中文翻译：

预后不良的活动性大血管炎患者的白细胞介素-1通路：纵向转录组分析

大血管血管炎（LVV）的特点是复发率高。由于 LVV 疾病状态的准确评估可能很困难，因此需要用于初始风险分层的准确预后标志物。我们对 LVV 患者的下一代 RNA 测序数据进行了全面的纵向调查，以探索与临床特征相关的有用生物标志物。

更新日期：2021-07-04

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