Abstract

The genus Paraconiothyrium has worldwide distribution with diverse host habitats and exhibits potential utilisation as biocontrol agent, bioreactor and antibiotic producer. In this review, we firstly comprehensively summarise the current taxonomic status of Paraconiothyrium species, including their category names, morphological features, habitats, and multigene phylogenetic relationships. Some Paraconiothyrium species possess vital biological functions and potential applications in medicine, agriculture, industry, and environmental protection. A total of 147 secondary metabolites have been reported so far from Paraconiothyrium, among which 95 are novel. This paper serves to provide an overview of their diverse structures with chemical classification and biological activities. To date, 27 species of Paraconiothyrium have been documented; however, only seven have been investigated for their secondary metabolites or biological functions. Our review is expected to draw more attention to this genus for providing a taxonomic reference, discovering extensive biological functions, and searching in-depth for new bioactive natural products.

摘要

Paraconiothyrium属在全球范围内分布，具有不同的寄主栖息地，并具有作为生物防治剂、生物反应器和抗生素生产者的潜在用途。在这篇综述中，我们首先全面总结了副棘球藻属物种的分类现状，包括它们的类别名称、形态特征、栖息地和多基因系统发育关系。一些副棘球藻属物种具有重要的生物学功能和在医学、农业、工业和环境保护方面的潜在应用。迄今为止，共报告了 147 种次生代谢物来自副棘球藻，其中95篇是小说。本文旨在概述其具有化学分类和生物活性的不同结构。迄今为止，已记录了27 种Paraconiothyrium；然而，只有七种被研究过其次生代谢物或生物学功能。我们的评论有望引起对该属的更多关注，以提供分类学参考，发现广泛的生物学功能，并深入寻找新的生物活性天然产物。