Brazilian Journal of Microbiology ( IF 2.1 ) Pub Date : 2021-07-03 , DOI: 10.1007/s42770-021-00554-8 Zhi-Min Hu 1 , Lan-Lan Wang 2 , Liang Zou 2 , Zhong-Ju Chen 3 , Yang Yi 4 , Qin-Bin Meng 5 , Yan Feng 6
Pulmonary mucormycosis and aspergillosis with disseminated mucormycosis involving gastrointestinalin is a very rare but lethal infection leading to extreme mortality. Herein, we present a unique case of pulmonary coinfection with Cunninghamella bertholletiae and Aspergillus flavus, with disseminated mucormycosis involving the jejunum caused by C. bertholletiae in an acute B-lymphocytic leukemia (B-ALL) patient with familial diabetes. Early administration of active antifungal agents at optimal doses and complete resection of all infected tissues led to improved therapeutic outcomes.
中文翻译:
急性 B 淋巴细胞白血病患者合并感染肺毛霉菌病和曲霉病与涉及胃肠道的播散性毛霉菌病
肺毛霉菌病和曲霉菌病伴有涉及胃肠道的播散性毛霉菌病是一种非常罕见但致命的感染,可导致极高的死亡率。在此,我们介绍了一个独特的肺部合并感染病例,该病例与Cunninghamella bertholletiae和黄曲霉共感染,在患有家族性糖尿病的急性 B 淋巴细胞白血病 (B-ALL) 患者中,由C.bertholletiae引起的涉及空肠的播散性毛霉菌病。早期给予最佳剂量的活性抗真菌药物并完全切除所有感染组织可改善治疗效果。