Negative emotionality (NE) and multiple cognitive vulnerabilities (CVs) (negative inferential style, brooding, self-criticism, dependency, dysfunctional attitudes) independently predict internalizing outcomes. The present study examined whether NE and CVs could be structurally integrated into a common factor reflecting shared variance across risks, and specific factors reflecting unique variance in risks. We evaluated the validity and utility of this integrated model via prospective prediction of future depression and anxiety compared to alternative models (NE and CVs individually, a correlated factor model). Youth from a large community sample (N = 571; M = 13.58 years old; 55% girls, 44% boys) reported on NE and CVs. Depression and anxiety symptoms based on youth report, and disorder onset based on youth and caregiver diagnostic interviews were assessed over a 1½ years follow-up. Results supported a structural model including a general NE-CV dimension and specific dimensions for NE, common cognitive risk, negative inferential style, and brooding; model invariance was obtained from late childhood through late adolescence and for girls and boys. The integrated general NE-CV factor more consistently and strongly predicted future depressive (β = 0.58) and anxiety (β = 0.56) symptoms, and onsets of depression (OR = 1.81) and anxiety (OR = 2.23) relative to NE and CV risk dimensions across alternative models (ps < .01). The general NE-CV dimension represents an important means to efficiently represent transdiagnostic risk for internalizing outcomes among youth.

消极情绪 (NE) 和多种认知脆弱性 (CV)（消极推理风格、沉思、自我批评、依赖、功能失调的态度）独立预测内化结果。本研究检验了 NE 和 CV 是否可以在结构上整合成一个共同因素，反映跨风险的共享差异，以及反映风险独特差异的特定因素。我们通过与替代模型（分别是 NE 和 CV，相关因素模型）相比对未来抑郁和焦虑的前瞻性预测来评估该集成模型的有效性和实用性。来自大型社区样本的青年（N  = 571；M = 13.58 岁；55% 的女孩，44% 的男孩）报告了 NE 和 CV。在 1.5 年的随访中评估了基于青年报告的抑郁和焦虑症状，以及基于青年和护理人员诊断访谈的疾病发作。结果支持一个结构模型，包括一般的 NE-CV 维度和 NE 的特定维度、常见认知风险、消极推理风格和沉思；模型不变性是从童年后期到青春期后期以及女孩和男孩获得的。综合的一般 NE-CV 因子更一致和强烈地预测未来的抑郁 (β = 0.58) 和焦虑 (β = 0.56) 症状，以及 相对于 NE 和 CV 风险的抑郁 ( OR  = 1.81) 和焦虑 ( OR = 2.23)的发作跨替代模型的维度 ( ps < .01)。一般的 NE-CV 维度代表了一种重要的手段，可以有效地表示青年内化结果的跨诊断风险。