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The Relationship Between the Gut Microbiome and Neurodegenerative Diseases
Neuroscience Bulletin ( IF 5.9 ) Pub Date : 2021-07-03 , DOI: 10.1007/s12264-021-00730-8
Xueling Zhu 1, 2 , Bo Li 1, 2 , Pengcheng Lou 1, 2 , Tingting Dai 1, 2 , Yang Chen 3 , Aoxiang Zhuge 1, 2 , Yin Yuan 1, 2 , Lanjuan Li 1, 2
Affiliation  

Many recent studies have shown that the gut microbiome plays important roles in human physiology and pathology. Also, microbiome-based therapies have been used to improve health status and treat diseases. In addition, aging and neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease, have become topics of intense interest in biomedical research. Several researchers have explored the links between these topics to study the potential pathogenic or therapeutic effects of intestinal microbiota in disease. But the exact relationship between neurodegenerative diseases and gut microbiota remains unclear. As technology advances, new techniques for studying the microbiome will be developed and refined, and the relationship between diseases and gut microbiota will be revealed. This article summarizes the known interactions between the gut microbiome and neurodegenerative diseases, highlighting assay techniques for the gut microbiome, and we also discuss the potential therapeutic role of microbiome-based therapies in diseases.



中文翻译:

肠道微生物群与神经退行性疾病的关系

最近的许多研究表明,肠道微生物组在人类生理学和病理学中起着重要作用。此外,基于微生物组的疗法已被用于改善健康状况和治疗疾病。此外,衰老和神经退行性疾病,包括阿尔茨海默病和帕金森病,已成为生物医学研究的热点。一些研究人员探索了这些主题之间的联系,以研究肠道微生物群在疾病中的潜在致病或治疗作用。但神经退行性疾病与肠道微生物群之间的确切关系仍不清楚。随着技术的进步,研究微生物组的新技术将得到发展和完善,疾病与肠道微生物群之间的关系将被揭示。

更新日期:2021-07-04
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