Treating patients with progressive supranuclear palsy (PSP) is both effective and rewarding. This review aims to share our experience in the proactive management of PSP, considering the patient, the family and the medical context in which the illness unfolds. There are many opportunities to assist your patients, ameliorate their symptoms, reduce their risks and harm, and guide them through the complex medical, social and legal minefield that characterises life with chronic neurological illness. We summarise the challenges of early diagnosis, consider PSP mimics and the role of investigations in excluding these, and discuss the available pharmacological and non-pharmacological treatment strategies to tackle the common and challenging symptoms of PSP. The best treatment will be patient centred and as part of a multidisciplinary team.

中文翻译：

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进行性核上性麻痹：诊断和治疗

治疗进行性核上性麻痹 (PSP) 患者既有效又有益。本综述旨在分享我们在主动管理 PSP 方面的经验，考虑到患者、家庭和疾病发生的医疗背景。有很多机会可以帮助您的患者，改善他们的症状，降低他们的风险和伤害，并引导他们度过复杂的医疗、社会和法律雷区，这些雷区是慢性神经疾病患者的生活特征。我们总结了早期诊断的挑战，考虑了 PSP 模拟和调查在排除这些方面的作用，并讨论了可用的药物和非药物治疗策略来解决 PSP 的常见和具有挑战性的症状。最好的治疗将以患者为中心，并作为多学科团队的一部分。