当前位置: X-MOL 学术Photochem. Photobiol. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Efficacy of Adjunctive Antimicrobial Photodynamic Therapy to Mechanical Debridement in the Treatment of Peri-implantitis or Peri-implant Mucositis in Smokers: A Systematic Review and Meta-analysis
Photochemistry and Photobiology ( IF 2.6 ) Pub Date : 2021-07-01 , DOI: 10.1111/php.13481
Rojin Shahmohammadi 1 , Shima Younespour 2 , Mojgan Paknejad 1 , Nasim Chiniforush 3, 4 , Mohadeseh Heidari 5
Affiliation  

This systematic review and meta-analysis aimed to determine whether adjunctive use of antimicrobial photodynamic therapy (a-PDT) in peri-implant diseases improves clinical outcomes in smokers. An electronic search was performed in MEDLINE (through PubMed), Scopus, Cochrane Library, Embase, Web of Science and Google Scholar. The primary outcome measures were bleeding on probing (BOP) and pocket depth (PD). Plaque index (PI) was the secondary outcome. Four RCTs, (188 participants) comprised of 118 cigarette smokers, 38 E-cig smokers and 32 water pipe smokers with follow-up periods ranged from 6 weeks to 6 months were recruited. All trials applied diode laser in one session with wavelengths ranged from 660 to 670 nm. There was a significant difference between mechanical debridement (MD)+a-PDT and MD alone groups in PD (WMD = −1.26 mm, 95% CI: −2.19 to −0.32, P = 0.01) and PI (WMD = −10.60%, 95% CI: −14.46 to −6.74, P < 0.001) at 3-month follow-up. However, a great amount of heterogeneity was observed (PD: χ2 = 199.19, I2 = 98%, P < 0.001 and PI: χ2 = 25.63, I2 = 84.4%, P < 0.001). Due to methodological heterogeneity and small number of studies, this systematic review was unable to reach conclusive evidence in regards of adjunctive a-PDT efficacy in improving clinical parameters in smokers.

中文翻译:

辅助抗菌光动力疗法对机械清创治疗吸烟者种植体周围炎或种植体周围粘膜炎的疗效:系统评价和荟萃分析

这项系统评价和荟萃分析旨在确定在种植体周围疾病中辅助使用抗微生物光动力疗法 (a-PDT) 是否可以改善吸烟者的临床结果。在 MEDLINE(通过 PubMed)、Scopus、Cochrane 图书馆、Embase、Web of Science 和 Google Scholar 中进行了电子搜索。主要结局指标是探诊出血 (BOP) 和口袋深度 (PD)。斑块指数(PI)是次要结果。招募了四项随机对照试验(188 名参与者),包括 118 名吸烟者、38 名电子烟吸烟者和 32 名水管吸烟者,随访期从 6 周到 6 个月不等。所有试验都在一个疗程中应用了二极管激光器,波长范围为 660 至 670 nm。在 PD 中,机械清创 (MD)+a-PDT 和 MD 单独组之间存在显着差异 (WMD = -1.26 mm, 95% CI: -2.P  = 0.01)和 PI(WMD = -10.60%,95% CI:-14.46 至 -6.74,P  < 0.001)在 3 个月的随访中。然而,观察到大量的异质性(PD:χ 2 = 199.19,I 2 = 98%,P  < 0.001 和 PI:χ 2 = 25.63,I 2 = 84.4%,P  < 0.001)。由于方法学异质性和研究数量较少,该系统评价无法就辅助 a-PDT 改善吸烟者临床参数的功效得出结论性证据。
更新日期:2021-07-01
down
wechat
bug