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Changes in Brain Functional and Effective Connectivity After Treatment for Breast Cancer and Implications for Intervention Targets
Brain Connectivity ( IF 2.4 ) Pub Date : 2022-05-12 , DOI: 10.1089/brain.2021.0049
Nicholas S Phillips 1, 2 , Vikram Rao 3 , Lorie Kmetz 3 , Ruben Vela 3, 4 , Sarah Medick 3 , Kevin Krull 1, 2 , Shelli R Kesler 3, 4, 5
Affiliation  

Background: Patients with breast cancer frequently report cognitive impairment both during and after completion of therapy. Evidence suggests that cancer-related cognitive impairments are related to widespread neural network dysfunction. The default mode network (DMN) is a large conserved network that plays a critical role in integrating the functions of various neural systems. Disruption of the network may play a key role in the development of cognitive impairment.

中文翻译:


乳腺癌治疗后大脑功能和有效连接的变化以及对干预目标的影响



背景:乳腺癌患者经常在治疗期间和完成后报告认知障碍。有证据表明,癌症相关的认知障碍与广泛的神经网络功能障碍有关。默认模式网络(DMN)是一个大型保守网络,在整合各种神经系统的功能方面发挥着至关重要的作用。网络中断可能在认知障碍的发展中发挥关键作用。
更新日期:2022-05-16
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