Background: Patients with breast cancer frequently report cognitive impairment both during and after completion of therapy. Evidence suggests that cancer-related cognitive impairments are related to widespread neural network dysfunction. The default mode network (DMN) is a large conserved network that plays a critical role in integrating the functions of various neural systems. Disruption of the network may play a key role in the development of cognitive impairment.

中文翻译：

---

乳腺癌治疗后大脑功能和有效连接的变化以及对干预目标的影响


背景：乳腺癌患者经常在治疗期间和完成后报告认知障碍。有证据表明，癌症相关的认知障碍与广泛的神经网络功能障碍有关。默认模式网络（DMN）是一个大型保守网络，在整合各种神经系统的功能方面发挥着至关重要的作用。网络中断可能在认知障碍的发展中发挥关键作用。