Background: To improve treatment outcomes of patients with schizophrenia, research efforts have focused on identifying brain-based markers of treatment response. Personal characteristics regarding disease-related behaviors likely stem from interindividual variability in the organization of brain functional systems. This study aimed to track dimension-specific changes in psychotic symptoms following risperidone treatment using individual-level functional connectivity (FC).

中文翻译：

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使用个体水平的功能连接跟踪利培酮治疗首发精神分裂症的积极和消极症状改善

背景：为了改善精神分裂症患者的治疗结果，研究工作集中在识别基于大脑的治疗反应标志物。关于疾病相关行为的个人特征可能源于大脑功能系统组织的个体差异。本研究旨在使用个体水平的功能连接 (FC) 跟踪利培酮治疗后精神病症状的维度特异性变化。