Previous results demonstrated that neuromuscular electrical stimulation (NMES) with various configurations could induce different activity at both the central and peripheral levels. Although NMES generating different peripheral movements have been studied, it is still unclear whether the difference in NMES-induced cortical activity is due to movement- or stimulation- related differences. Because NMES-induced cortical activity impacts motor function recovery, it is essential to know when NMES with various configurations evoke the same movement, whether the induced cortical activity is still different. Four NMES configurations: 1) Eight-let Frequency Trains, 2) Doublet frequency trains (DFT), 3) Constant-frequency trains with narrow-pulse, and 4) wide-pulse, were delivered to the right biceps brachii muscle in nine healthy young adults. We adjusted the intensities of these NMES to evoke the same elbow flexion and compared the cortical activities over sensorimotor regions. Our results showed that the four NMES patterns induced different beta-band Event-Related Desynchronization (ERD), with the DFT providing the strongest ERD value given the same NMES-induced elbow flexion (p <; 0.05). This difference is possibly due to NMES with different configuration activated in the amount of afferent proprioceptive fibers. Our pilot study suggests that the NMES-induced beta-band ERD may be an additional factor to consider when selecting the NMES configuration for a better motor function recovery.

中文翻译：

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各种神经肌肉电刺激引起的事件相关 Beta 脑电图变化：一项试点研究


先前的结果表明，不同配置的神经肌肉电刺激（NMES）可以在中枢和外周水平诱导不同的活动。尽管已经研究了 NMES 产生不同的外周运动，但仍不清楚 NMES 诱导的皮层活动的差异是否是由于运动或刺激相关的差异造成的。由于 NMES 诱发的皮层活动影响运动功能恢复，因此有必要了解当不同配置的 NMES 诱发相同的运动时，诱发的皮层活动是否仍然不同。四种 NMES 配置：1) 八连频率训练、2) 双频率训练 (DFT)、3) 窄脉冲恒频训练和 4) 宽脉冲，被传递到 9 名健康人的右肱二头肌年轻人。我们调整这些 NMES 的强度以引起相同的肘部弯曲，并比较感觉运动区域的皮质活动。我们的结果表明，四种 NMES 模式引起不同的 β 波段事件相关去同步 (ERD)，在相同的 NMES 引起的肘部弯曲的情况下，DFT 提供最强的 ERD 值 (p <; 0.05)。这种差异可能是由于 NMES 在传入本体感觉纤维的数量上激活的配置不同。我们的初步研究表明，在选择 NMES 配置以实现更好的运动功能恢复时，NMES 诱导的 β 带 ERD 可能是需要考虑的另一个因素。