Background

Over the previous two decades, the lifetime prevalence of cannabis use has risen among Mexico’s population.

Aims

Estimate the sex- and age-specific rates of onset of cannabis use over time.

Design

Five nationally representative cross-sectional surveys, the Mexican National Surveys of Addictions (1998, 2002, 2008, 2012) and the Mexican National Survey on Drugs, Alcohol, and Tobacco Consumption (2016).

Setting

Mexico. Participants: Pooled sample of 141,342 respondents aged between 12 and 65 years of which 44.6%(n=61,658) are male and 56.4% (n=79,684) are female.

Measurements

We estimated the age-specific rates of onset of cannabis as the conditional rate of consuming cannabis for the first time at a specific age.

Methods

Time-to-event flexible-parametric models with spline specifications of the hazard function. Stratified analysis by sex and control for temporal trends by year of data collection or decennial birth cohort.

Findings

Age-specific rates of onset of cannabis use per 1,000 individuals increased over time for females and males. Peak rates of onset of cannabis use per 1,000 ranged from 0.935 (95%CI= [0.754,1.140]) in 1998, to 5.390 (95%CI= [4.910,5.960]) in 2016 for females; and from 7.510 (95%CI= [5.516, 10.355]) in 1998, to 26.100 (95%CI= [23.162,30.169]) in 2016 for males. Across decennial birth-cohorts, peak rates of onset of cannabis use per 1,000 individuals for females ranged from 0.234 (95%CI= [0.080,0.739]) for those born in the 1930s, to 14.600 (95%CI= [13.200,16.100]) for those born in the 1990s; and for males, from 4.900 (95%CI= [0.768, 7.947]) for those born in the 1930s, to 38.700 (95%CI= [32.553,66.341]) for those born in the 1990s. Conclusion

Rates of onset of cannabis increased over the previous two decades for both females and males but remained higher for males. Across recent cohorts, the rates of onset have increased at a faster rate among females than males.

中文翻译：

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墨西哥不同年龄阶段吸食大麻的比率

背景

在过去的二十年中，墨西哥人口中大麻的终生使用率有所上升。

目标

估计随时间推移的特定性别和年龄的大麻使用发病率。

设计

五项具有全国代表性的横断面调查：墨西哥国家成瘾调查（1998 年、2002 年、2008 年、2012 年）和墨西哥国家毒品、酒精和烟草消费调查（2016 年）。

环境

墨西哥。参与者：汇集了 141,342 名年龄在 12 至 65 岁之间的受访者样本，其中 44.6% (n=61,658) 为男性，56.4% (n=79,684) 为女性。

测量

我们将特定年龄的大麻发病率估计为在特定年龄首次吸食大麻的有条件率。

方法

具有危险函数样条规范的事件发生时间灵活参数模型。按性别进行分层分析，并按数据收集年份或十年出生队列控制时间趋势。

发现

随着时间的推移，女性和男性每 1000 人中特定年龄的大麻使用率有所增加。女性每 1,000 人吸食大麻的峰值比率从 1998 年的 0.935 (95%CI= [0.754,1.140]) 到 2016 年的 5.390 (95%CI= [4.910,5.960])；男性从 1998 年的 7.510 (95% CI= [5.516, 10.355]) 增加到 2016 年的 26.100 (95% CI= [23.162,30.169])。在十年出生队列中，女性每 1,000 人吸食大麻的峰值发生率从 1930 年代出生的 0.234 (95%CI= [0.080,0.739]) 到 14.600 (95%CI= [13.200,16.100) ]) 适合 20 世纪 90 年代出生的人；对于男性来说，从 1930 年代出生的 4.900 (95%CI= [0.768, 7.947]) 到 1990 年代出生的 38.700 (95%CI= [32.553,66.341])。结论

在过去的二十年中，女性和男性吸食大麻的比率均有所增加，但男性的吸食率仍然较高。在最近的队列中，女性发病率的增加速度快于男性。