Spontaneous intracerebral hemorrhage occurs in an estimated 10% of stroke patients, with high rates of associated mortality. Portable diagnostic technologies that can quickly and noninvasively detect hemorrhagic stroke may prevent unnecessary delay in patient care and help rapidly triage patients with ischemic versus hemorrhagic stroke. As such, the authors aimed to develop a rapid and portable eddy current damping (ECD) hemorrhagic stroke sensor for proposed in-field diagnosis of hemorrhagic stroke.

A tricoil ECD sensor with microtesla-level magnetic field strengths was constructed. Sixteen gelatin brain models with identical electrical properties to live brain tissue were developed and placed within phantom skull replicas, and saline was diluted to the conductivity of blood and placed within the brain to simulate a hemorrhage. The ECD sensor was used to detect modeled hemorrhages on benchtop models. Data were saved and plotted as a filtered heatmap to represent the lesion location. The individuals performing the scanning were blinded to the bleed location, and sensors were tangentially rotated around the skull models to localize blood. Data were also used to create heatmap images using MATLAB software.

The sensor was portable (11.4-cm maximum diameter), compact, and cost roughly $100 to manufacture. Scanning time was 2.43 minutes, and heatmap images of the lesion were produced in near real time. The ECD sensor accurately predicted the location of a modeled hemorrhage in all (n = 16) benchtop experiments with excellent spatial resolution.

Benchtop experiments demonstrated the proof of concept of the ECD sensor for rapid transcranial hemorrhagic stroke diagnosis. Future studies with live human participants are warranted to fully establish the feasibility findings derived from this study.

估计有 10% 的中风患者会发生自发性脑出血，相关死亡率很高。可以快速、无创地检测出血性中风的便携式诊断技术可以防止不必要的患者护理延误，并有助于快速对缺血性和出血性中风患者进行分类。因此，作者旨在开发一种快速便携式涡流阻尼 (ECD) 出血性中风传感器，用于提议的出血性中风的现场诊断。

构建了具有微特斯拉级磁场强度的三线圈 ECD 传感器。开发了与活脑组织具有相同电特性的 16 个明胶脑模型，并将其放置在幻影颅骨复制品中，将盐水稀释至血液的导电性并放置在大脑内以模拟出血。ECD 传感器用于检测台式模型上的建模出血。数据被保存并绘制为过滤热图以表示病变位置。执行扫描的个体不知道出血位置，传感器围绕头骨模型切向旋转以定位血液。数据还用于使用 MATLAB 软件创建热图图像。

该传感器便于携带（最大直径为 11.4 厘米）、结构紧凑，制造成本约为 100 美元。扫描时间为 2.43 分钟，几乎实时生成病变的热图图像。ECD 传感器以出色的空间分辨率准确预测了所有 (n = 16) 台​​式实验中建模出血的位置。

台式实验证明了 ECD 传感器用于快速经颅出血性中风诊断的概念证明。未来有必要对真人参与者进行研究，以充分确定从这项研究中得出的可行性结果。