Differences in activated clotting time and total unfractionated heparin dose during pulmonary vein isolation in patients on different anticoagulation therapy,Clinical Cardiology

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Differences in activated clotting time and total unfractionated heparin dose during pulmonary vein isolation in patients on different anticoagulation therapy
Clinical Cardiology ( IF 2.7 ) Pub Date : 2021-07-01 , DOI: 10.1002/clc.23681
Ivan Zeljkovic ₁ , Sandro Brusich ₂ , Daniel Scherr ₃ , Vedran Velagic ₄ , Vassil Traykov ₅ , Andrej Pernat ₆ , Ante Anic ₇ , Janko Szavits Nossan ₈ , Matevz Jan ₉ , Zoran Bakotic ₁₀ , Borka Pezo Nikolic ₄ , Vjekoslav Radeljic ₁ , Ana Bojko ₁ , Ivica Benko _{1,

11} , Sime Manola _{1,

11} , Nikola Pavlovic _{1,

11}

Affiliation

Department of Cardiology, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia.
Department of Cardiology, University Hospital Centre Rijeka, Rijeka, Croatia.
Department of Cardiology, Medical University Graz, Graz, Austria.
Department of Cardiology, University Hospital Centre Zagreb, Zagreb, Croatia.
Department of Cardiology, Acibadem City Clinic Tokuda Hospital, Sofia, Bulgaria.
Department of Cardiology, University Hospital Centre Ljubljana, Ljubljana, Slovenia.
Department of Cardiology, University Hospital Centre Split, Split, Croatia.
Department of Cardiology, Magdalena Clinic, KrapinskeToplice, Croatia.
Department of Cardiac Surgery, University Hospital Centre Ljubljana, Ljubljana, Slovenia.
Department of Cardiology, General Hospital Zadar, Zadar, Croatia.
Department of Cardiology, University Hospital Dubrava, Zagreb, Croatia.

Periprocedural pulmonary vein isolation (PVI) anticoagulation requires balancing between bleeding and thromboembolic risk. Intraprocedural anticoagulation is monitored by activated clotting time (ACT) with target value >300 s, and there are no guidelines specifying an initial unfractionated heparin (UFH) dose.

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