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Maternal separation impairs mother's cognition 1 month beyond the separation
International Journal of Developmental Neuroscience ( IF 1.8 ) Pub Date : 2021-07-01 , DOI: 10.1002/jdn.10138
Sara Joushi 1 , Vahid Sheibani 1 , Khadijeh Esmaeilpour 1 , José Francis-Oliveira 2 , Zahra Taherizadeh 1 , Fatemeh Mohtashami Borzadaran 1
Affiliation  

Separation of pups from their dam during the infancy not only has detrimental effects on the pups' brain but also affects dams' behavior. Postpartum stress may affect mothers' cognitive functions. In the present study, by using a 180-min day−1 maternal separation (MS) paradigm, we assessed anxiety-like behavior and locomotor activity of rat dams which experienced separation from postnatal day (PND) 1 until weaning. We tried for the first time to clarify whether such separation impairs dam's performance in the Morris water maze.

中文翻译:

产妇分居后1个月影响母亲的认知

在婴儿期将幼崽与母鼠分开不仅会对幼崽的大脑产生不利影响,还会影响母鼠的行为。产后压力可能会影响母亲的认知功能。在本研究中,通过使用 180 分钟第-1天母体分离 (MS) 范式,我们评估了从产后第 1 天 (PND) 到断奶经历分离的大鼠水坝的焦虑样行为和运动活动。我们首次尝试澄清这种分离是否会损害大坝在莫里斯水迷宫中的性能。
更新日期:2021-07-01
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