ABSTRACT

Background

Mindfulness has been found to be a helpful approach for some peole who experience psychosis.

Methods

We used data from a prior exploratory clinical trial, to compare the effects on psychotic symptoms of six months of standard psychiatric rehabilitation versus six months of standard psychiatric rehabilitation combined with weekly mindfulness sessions. 52 patients from a community rehabilitation center were randomly allocated to Integrated Rehabilitation Treatment (IRT) or IRT enhanced with Mindfulness Based Interventions (IRT+MBI). Measures comprised a clinical record form and the PANSS interview scored according to the five-factor model of Wallwork. Raters were blinded to treatment allocation.

Results

Both groups reduced their scores in the Depression factor (IRT+MBI: F = 5.29, p = .026, Ƞ² = .096, IRT: F = 4.51, p = .039, Ƞ² = .083), IRT+MBI also reduced their scores in the Negative (F = 32.21, p < .001, Ƞ² = .392) and Excited (F = 4.87, p = .032, Ƞ² = .089) factors. Simple effect analysis at post-treatment showed significant differences in the Negative factor in favor of IRT+MBI (F = 4.67, p = .035, Ƞ² = .085).

Discussion

Mindfulness did not increase the frequency of positive symptoms but it did reduce negative symptoms. The lack of an effective treatment for negative psychotic symptoms underscores the clinical importance of the findings.

中文翻译：

---

正念对精神病症状的影响：来自随机临床试验的见解

摘要

背景

正念被发现对一些患有精神病的人来说是一种有用的方法。

方法

我们使用来自先前探索性临床试验的数据来比较六个月标准精神病康复与六个月标准精神病康复结合每周正念课程对精神病症状的影响。来自社区康复中心的 52 名患者被随机分配到综合康复治疗 (IRT) 或通过正念干预增强的 IRT (IRT+MBI)。措施包括临床记录表和根据 Wallwork 的五因素模型评分的 PANSS 访谈。评估者对治疗分配不知情。

结果

两组都降低了他们在抑郁因子上的分数（IRT+MBI：F = 5.29，p = .026 ， ^σ2 = .096，IRT：F = 4.51，p = .039， ^{σ2 =} .083），IRT+MBI也降低了他们在消极 ( F = 32.21, p < .001, ? ^{2 =} .392 ) 和兴奋 ( F = 4.87, p = .032, ? ^{2 =} .089 ) 因素中的分数。治疗后的简单效应分析显示，有利于 IRT+MBI 的负面因素存在显着差异（F = 4.67，p = .035，σ² = .085)。

讨论

正念并没有增加阳性症状的频率，但它确实减少了阴性症状。对阴性精神病症状缺乏有效的治疗强调了这些发现的临床重要性。