The biological damage caused by the environmental factors such as radiation and its control methods are one of the frontiers of life science research that has received widespread attention. Ionizing radiation can directly interact with target molecules (such as DNA, proteins and lipids) or decomposed by radiation from water, leading to changes in oxidative events and biological activities in cells. Liver is a radiation-sensitive organ, and its radiosensitivity is second only to bone marrow, lymph, gastrointestinal tissue, gonads, embryos and kidneys. In addition, as a key organ of mammals, liver performs a series of functions, including the production of bile, the metabolism of nutrients, the elimination of waste, the storage of glycogen, and the synthesis of proteins. Therefore, liver is prone to various pathophysiological changes. In this review, the effects of radiation on liver injury, its pathogenesis, bystander effect and the natural traditional Chinese medicine to protect the radiation induced liver damage are discussed.

辐射等环境因素引起的生物损伤及其控制方法是目前受到广泛关注的生命科学研究前沿之一。电离辐射可以直接与目标分子（如 DNA、蛋白质和脂质）相互作用或被水的辐射分解，导致细胞内氧化事件和生物活性发生变化。肝脏是辐射敏感器官，其辐射敏感性仅次于骨髓、淋巴、胃肠组织、性腺、胚胎和肾脏。此外，作为哺乳动物的重要器官，肝脏还具有一系列功能，包括产生胆汁、代谢营养物质、排除废物、储存糖原和合成蛋白质。因此，肝脏容易发生各种病理生理变化。在本次审查中，